C. Sep 28, 2011 · CAS: 25013-15-4; Chemical Formula: CH 3 C 6 H 4 CH=CH 2. STEL value 2. 1000 Table Z-Shipyards. Freezing point/melting point. The Permissible Exposure Limit (PEL) of 200 ppm is considered an acceptable level of exposure as a time-weighted average for an 8-hour workday. e. . OSHA Directive TED 01-00-015 [TED 1-0. Sampling volume (TWA) * 1910. Workers may be harmed from exposure . 1028). , R= 0. Chemical structure: TLV–TWA, 20 ppm. Apr 6, 2021 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. Toluene vapor has a sharp or sweet odor, which is a sign of exposure. is recommended to protect workers from toluene-induced neurologic effects (i. The National Institute for Occupational Safety and Health (NIOSH) has set a recommended limit of 100 ppm for toluene in air averaged over a 10-hour workday. Cal/OSHA sets Permissible Exposure Limits (PELs) for the amounts of certain chemicals in workplace air. 5 ppm ; ethylbenzene OSHA PEL PEL 100 ppm 435 mg/m3 ; TWA value 100 ppm 435 mg/m3 ; STEL value 125 ppm 545 mg/m3 ; ACGIH TLV TWA value 20 ppm ; Toluene OSHA PEL TWA value 100 ppm 375 mg/m3 ; STEL value 150 ppm 560 mg/m3 ; max. CAS: 108-88-3; Chemical Formula: C 6 H 5 CH 3. Exposures to 200 ppm for 8 hours caused mild fatigue, weakness, Toluene exposure may cause liver and kidney damage. See OSHA Z-1 and Z-2 tables. 6H. Reasons for Citation Toluene is on the Right to Know Hazardous Substance List because it is cited by OSHA, ACGIH, DOT, NIOSH, DEP, IARC, IRIS, NFPA and EPA. Apr 14, 2021 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. The NPG gives general industrial hygiene information for hundreds of chemicals/classes. Flash point. Molecular weight. 96-111. In this method EtO reacts with HBr to form. Colorless to pale-yellow solid or liquid (above 71°F) with a sharp, pungent odor. for 2,4-TDI was replaced with an 8-h TWA PEL of 0. The revised standard reduces the permissible exposure limit (PEL) from 10 parts benzene per million parts of air (10 ppm) to an eight (8)-hour time-weighted average (TWA) of 1 ppm and a short-term exposure Feb 11, 2014 · Section 5 (a) (1) of the Occupational Safety and Health Act, the General Duty Clause, may used to cite deflagration, other fire, or explosion hazards where combustible dust hazards exist within dust control systems or other containers. 8-47, Table N1) concurs with the retention of this limit. Cal/OSHA's PEL for toluene is 100 ppm. NIOSH REL (United States, 6/2009). 75 L) ****120 min (6 L) Toluene's odor is discernable at a concentration of 8 ppm, which is 25 times less than the OSHA PEL (200 ppm); therefore, odor generally provides adequate warning of acutely hazardous concentrations. 1. Apr 14, 2021 · CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak PEL-TWA . 11 Revision Date: 05/11/2022 SDS Number: 100000002760 4 / 14 Toluene Carbon dioxide (CO2) Dry chemical Unsuitable extinguishing media : High volume water jet Specific hazards during fire-fighting : Do not allow run-off from fire fighting to enter drains or water courses. 02 ppm for TDI. See annual publication for most recent information. To help keep workers National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 100 ppm (375 mg/m 3) 10-hour TWA; 150 ppm (560 mg/m 3) STEL. The NPG clearly presents key data for chemicals or substance groupings (such as cyanides Mar 25, 2024 · NIOSH 1606 (fully validated) Notes. STEL (15-minute time-weighted average not to be exceeded is 565,000 μg/m3). Jan 4, 2021 · A colorless liquid with an odor of lemon. Apr 11, 2022 · The Occupational Safety and Health Administration (OSHA) has determined the acceptable level of occupational exposure to toluene for people in the workplace. 04 mg/m. 31. 08 mg/kg/day . Exposure to very high levels (15,000 to 30,000 ppm) for a short time may cause mental confusion, loss of coordination, and unconsciousness. Hazardous combustion prod-ucts OSHA PEL . Recommended air volume The former OSHA limit for toluene-2,4-diisocyanate (TDI) was a ceiling of 0. NIOSH (Ex. Ship samples overnight with cold-packs as soon as possible. V can be substituted in the formulas for converting between mg/m 3 and ppm. Toxic effects (This section is for information only and should not be taken as a basis for OSHA policy. Special requirements. Abstract: Amendment of existing standard for Occupational Exposure to Benzene. Sep 14, 2023 · OSHA Permissible Exposure Limits: Toluene: 200 ppm TWA PEL 300 ppm Acceptable Ceiling Concentration 500 ppm Acceptable Maximum Peak Above the Acceptable Ceiling Concentration for an 8-hr Shift. *80 min (4L) **Peak sampling 1 min (0. 02 ppm (ceiling) Jul 21, 2008 · A PEL recommendation of. 01 and 0. unless adopted by a state OSHA such as Minnesota). There is no need to contact SLTC before sampling. Keep samples refrigerated when not in transit. Although no change was made to the Ceiling PEL for MDI, the valve for toluene-2,4-diisocyanate (2,4-TDI) became an 8-h TWA-PEL. Refinery workers are at risk for exposure to benzene, toluene, ethylbenzene, xylene (BTEX) and other volatile organic compounds (VOCs) from routine sampling and maintenance operations, releases from large bulk facilities, surface spills and pipeline leaks. OSHA has set a legal limit for workers of 200 ppm for toluene in air averaged over an 8-hour workday. 1 Attach the sampling equipment to the worker in such a manner that it well not interfere with work performance or safety. K ) For n = 1 V = RT / P. 8 Benzene was the 16th highest chemical in the ranking of production by volume for 1995. The Ceiling PEL of 0. Toluene’s odor is discernable at a concentration of 8 ppm, which is 25 times less than the OSHA PEL (200 ppm); therefore, odor generally provides adequate warning of acutely hazardous concentrations. The PELs are intended to protect the health of a person who is exposed every day over a working lifetime. Toxic effects (This section is for information only and should not be taken as the basis of OSHA policy. To view TLV and Documentation, you must be logged in as an ACGIH member 1 The PELs are 8-hour TWAs unless otherwise noted; a (C) designation denotes a ceiling limit. Thus, toluene at low concentrations may produce disturbances in dopaminergic mechanisms of the basal ganglia probably leading to Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. at or above 200°F. The TLV for toluene was established to protect Apr 19, 2021 · ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Toluene diisocyanate, 2,4 or 2,6- (or as a mixture). Wear eye protection when breaking off ends of flame-sealed glass sampling tubes. TDI, 2,4-TDI, 2,4-Toluene diisocyanate. 10. Essentially, a PEL is basically the same as a TLV/REL except PELs are actual OSHA regulations whereas TLV/RELs are not. CFR 1910. Submit as a separate sample, however, hydrogen bromide can be analyzed from the same sample. This is equal to 375 milligrams of toluene per cubic meter of air a This standard applies to the industry segments exempt from the 1 ppm 8-hour TWA and 5 ppm STEL of the benzene standard at 1910. Please indicate on the 91A which of these compounds are known to be present. CEIL: 300 ppm AMP: 500 ppm 10 minute(s). OSHA: Occupational Safety and Health Standards, Substance Safety Data Sheet and Technical Guidelines for Methylene Chloride. Method No. Att ach sampler t o personal sampling pump with flexible tubing. The lowest concentration that will cause immediate throat irritation is 3 ppm. NMAM also includes chapters on quality assurance, sampling, portable instrumentation, etc. Component ACGIH TLV OSHA PEL NIOSH Mexico OEL (TWA) Toluene TWA: 20 ppm (Vacated) TWA: 100 ppm (Vacated) TWA: 375 mg/m3 Ceiling: 300 ppm (Vacated) STEL: 150 ppm (Vacated) STEL: 560 mg/m 3 TWA: 200 ppm IDLH: 500 ppm TWA: 100 ppm TWA: 375 mg/m3 STEL: 150 ppm STEL: 560 mg/m TWA: 20 ppm Legend ACGIH - American Conference of Governmental Industrial The following information applies to Table 3, Permissible Exposure Limits (PELs) for Airborne Contaminants. Benzene: 1 ppm TWA* 5 ppm STEL* *Except industry segments for which 29 CFR 1910. TWA: 20 ppm 8 hour(s). NIOSH Manual of Analytical Methods (NMAM), Fourth Edition. atm / mol . 8 Safety Precautions: 2. (C n ÷ L n) Where: E m is the equivalent exposure for the mixture. Component ACGIH TLV OSHA PEL NIOSH IDLH Toluene TWA: 20 ppm (Vacated) TWA: 100 ppm (Vacated) TWA: 375 mg/m3 Ceiling: 300 ppm (Vacated) STEL: 150 ppm (Vacated) STEL: 560 mg/m3 TWA: 200 ppm IDLH: 500 ppm TWA: 100 ppm TWA: 375 mg/m3 STEL: 150 ppm STEL: 560 mg/m3 Component Quebec Mexico OEL (TWA) Ontario TWAEV Toluene TWA: 50 ppm TWA: 188 mg/m3 Dec 22, 2020 · CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak PEL-TWA: 50 ppm (245 mg/m³) REL-TWA: 50 ppm (245 mg/m³) TLV-TWA: 50 ppm [1997] PEL-TWA: 50 ppm (245 mg/m³) Toluene TWA: 20 ppm (Vacated) TWA: 100 ppm (Vacated) TWA: 375 mg/m3 Ceiling: 300 ppm (Vacated) STEL: 150 ppm (Vacated) STEL: 560 mg/m 3 TWA: 200 ppm IDLH: 500 ppm TWA: 100 ppm TWA: 375 mg/m3 STEL: 150 ppm STEL: 560 mg/m TWA: 20 ppm Legend ACGIH - American Conference of Governmental Industrial Hygienists OSHA - Occupational Safety and Health Toluene-2,4-diisocyanate. These isomers differ only in placement of two methyl groups on a benzene ring. 5 ppm Odor thresholds vary greatly. 5522. These OELs also apply Respirator Recommendations. Sampling volume (STEL/Peak/C) * Sampling flow rate (STEL/Peak/C) * Analytical method instruments: GC-ECD : Method reference: OSHA 65 (fully validated) Notes: Within ten hours after sampling, transfer filter to glass vial containing 2 mL deionized water. Safety and Health (NIOSH) Occupational/ Indoor air 375,000 μg/m3 Recommended exposure limits (RELs) are time-weighted average (TWA) concentrations for up to a 10-hour workday during a 40-hour work week. Table AC1 - Permissible Exposure LIMITS FOR CHEMICAL CONTAMINANTS Toluene diisocyanate is commonly used as a chemical intermediate in the production of polyurethane foams, elastomers, and coatings; paints; varnishes; wire enamels; sealants; adhesives; and binders. NIOSH recommends TWA of 375,000 μg/m3. The Occupational Safety and Health Administration (OSHA) has set a legal limit for workers of 200 ppm for toluene in air averaged over an 8 hour workday. Molecular formula: C 7 H 8. ) When updating its air contaminants standard in 1989, OSHA decreased this limit to 0. Synonyms: Aantisal 1a; Methacide; Methyl-benzene; Methylbenzol; Monomethyl benzene; Phenyl methane; Toluol; Tolu-sol. 12) 1. 05 mg/m³) TLV-TWA . 2 Follow all safety practices that apply to the work area being sampled. The central nervous system (CNS) is the primary target organ for toluene toxicity in both humans and animals for acute (short-term) and chronic (long Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. OTO –Ototoxicant. (k) See Table Z-2 for the exposure limits for any operations or sectors where the exposure limits in 1910. Personal Protective Equipment (PPE): To conduct combustible dust sampling, CSHOs shall wear non-spark workplace chemical exposure. Since in sensitized individuals, even concentrations below the OSHA PEL are capable of triggering the allergic response, the revised IDLH has not been based on data above the Federal OSHA permissible exposure limits (PEL). The report for the update work has been incorporated into the "Backup Data" section of this method as Section 4. Skin notation Y. 5 ppm based on acute inhalation toxicity data in animals [Duncan et al. Make sure that the glass fiber filter plug is firmly in contact with the silica gel before and after sampling. Standard Number: 1910. Toluene-2,4-Diisocyanate is a colorless to pale yellow liquid with a strong fruity odor. Boiling point. 036 mg/m3) as an 8-hour time-weighted average (TWA) and 0. 2. (Sections 4. TWA: 100 ppm 2. 95 mg/m3], respectively (29 CFR 1910. STEL: 150 ppm 15 minute(s). 11 ppm TWA. As with 2,4-TDI, it was found that long term sampling (240 min at 1 L/min) for MDI is feasible. The gas constant can have different values if the temperature and pressure are expressed in different units from those in the above equation (e. NIOSH has set a recommended limit of 100 ppm for toluene in air averaged over a 10-hour workday. 75 L) ****120 min (6 L) Apr 5, 2024 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. CDC: Fatal exposure to methylene chloride among bathtub refinishers - United States, 2000-2011. 2 Toxic effects (This section is for information only and should not be taken as the basis of OSHA policy. 005 ppm and a STEL of 0. Other. 2015 Page 1 of 8 Toluene, Reagent Grade lsECTION 1 : Identification of the substance/mixture and of the supplier Product name : Toluene, Reagent Grade Manufacturer/Supplier Trade name: Recommended uses of the product and uses restrictions on use: Toluene. Toluene is typically used in a mixture with other solvents and chemicals such as paint pigments. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910. A4 —Not Classifiable as a Human Carcinogen. Occupational Safety and Health Administration (OSHA) has set a legal toluene exposure limit for workers of 200 parts per million (ppm Mar 25, 2015 · PRODUCT NAME EXPOSURE LIMITS TOLUENE OSHA PEL Z2 (United States, 11/2006). Many workers are unaware of the potential hazards that chemicals present in their work environment, which makes them more vulnerable to injury. 500 ppm ; CLV 300 ppm ; TWA value 200 ppm ; ACGIH TLV TWA value 20 ppm ; Toluene is readily absorbed from the lungs, and most exposures to toluene occur by inhalation. 7. 75 L) ****120 min (6 L) Jan 6, 2024 · July 2010. 14 CAS: 108-88-3 RTECS: XS5250000. Exposure to toluene can cause eye and nose irritation, tiredness, confusion, euphoria, dizziness, headache, dilated pupils, tears, anxiety, muscle fatigue, insomnia, nerve damage, inflammation of the skin, and liver and kidney damage. DHHS (NIOSH) Publication No. 1000, Table Z-2 exposure limits apply. NIOSH/OSHA. Toluene (Methylbenzene, Toluol, Phenylmethane) The IDLH documents the criteria and information sources that have been used by NIOSH to determine immediately dangerous to life or health concentrations. Toluene affects the central nervous system, eyes, skin, respiratory system, liver, kidneys. P. ETHYLBENZENE OSHA PEL (United States, 11/2006). 1000 Table Z-2. 4. 02 ppm (0. There is evidence that exposure to toluene at work is Safety Data Sheet Toluene Version 1. OSHA Construction PEL is C-100 ppm (420 mg/m³) and OSHA Maritime PEL is 100 ppm (420 mg/m³) as an 8 hr TWA. (a) Parts of vapor or gas per million parts of contaminated air by volume at 25 °C and 760 torr. Break the ends of t he sampler imm ediat ely before sampling. 136. 75 L) ****120 min (6 L) PEL - The OSHA Permissible Exposure Limit is a regulatory limit for the concentration of a contaminant in workplace air. SummaryToluene is added to gasoline, used to produce benzene, and used as a. However, this standard was rescinded by court order in 1992. They are to be determined from breathing-zone air samples. December 1989. The ACGIH has an exposure limit for toluene of 100 ppm as an 8-hour TWA and 150 ppm as a 15-minute STEL; NIOSH OSHA Method 501 for ethylene oxide (EtO) was validated in 1985 and specifies collection of EtO using sampling tubes containing petroleum based charcoal coated with 10% hydrobromic acid (HBr). The values shown refer to the level as an 8h-TWA (8 hour time weighted average) unless otherwise noted, given in ppm (parts per million in contaminated air) unless otherwise noted. TOLUENE (diffusive sampler) 4000. 584) and NIOSH (Ex. TWA: 200 ppm 8 hour(s). TWA: 100 ppm 10 hour(s). Apr 13, 2021 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. (1) Ppm refers to parts of vapor or gas per million parts of air by volume, at 25 degrees C and 760 mm Hg pressure. 11. 1-3, p. Toluene. The toxicological review provides information on which these values are based. MMWR Morb Mortal Wkly Rep. It was also decided that carbon disulfide (CS 2 May 18, 2022 · PEL-C: 500 ppm. Incidentally, OSHA PELs adopted TLVs based on recommendations made by the ACGIH. 1962]. 14 mg/m3) as a short-term exposure limit. 14 mg/m3 for TDI. S. 61 (7):119-22, 2012. The ACGIH Threshold Limit Value (TLV) was established in 2006. 75 L) ****120 min (6 L) Apr 13, 2021 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. NIOSH: 100 ppm; STEL 150 ppm. 005 ppm [1985] PEL-TWA . 1026 are stayed or are otherwise not in effect. 8014-135SA: approx 5-300 ppm range, 8014-243U: approx 5-160 ppm range, 8014-135SB: approx 1-10 ppm, 8014-135SH: 0. NIOSH/CEC/ICPS: International Chemical Safety Cards - Toluene-2,6-diisocyanate. for toluene. 55 Table 1 and 29 CFR 1915. 2 . Oct 14, 2022 · The Panel re-evaluated the safety of toluene in nail polish in 2005 and confirmed its original conclusion. 1000 (d) (2) (i) In case of a mixture of air contaminants an employer shall compute the equivalent exposure as follows: E m = (C 1 ÷ L 1 + C 2 ÷ L 2) + . Procedure: Samples are collected by drawing known volumes of air through OSHA versatile sampler (OVS-2) tubes, each containing a glass fiber filter and two sections of XAD-2 adsorbent. The acrolein PEL remains a TWA of 0. 5 ppm ; TWA value 0. Isocyanates. May 12, 2022 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. The OSHA PEL for MDI is 0. 6 and 4. b This standard applies to any operations or sectors for which the Cadmium standard, 1910. 1052 App A. . Its vapor is heavier than air and Jun 23, 2023 · Monitoring Methods Used by OSHA; Analyte code (IMIS no. See 29 CFR 1926. 2-bromoethanol which is then extracted from the charcoal with dimethylformamide. g. METHOD: 4000, Issue 2 EVALUATION: FULL Issue 1: 15 August 1987 Issue 2: 15 August 1994 OSHA :200 ppm; C 300 ppm; P 500 ppm. Monitoring Methods Used by OSHA. 8-47, Table N1) both recommend a TWA of 0. Related Pages Exposure Limits. 108-88-3. Revised IDLH: 2. 3 Effective date : 01. NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 500 ppm. Skin notation N. 1. Analytical Procedure There was no OSHA-recommended sampling or analytical scheme for m-toluidine. 412 billion gallons in 2000. 2 mg/m3) as a ceiling limit. OSHA has Permissible Exposure Limits (PELs) for Methylene bisphenyl diisocyanate (MDI) and 2,4 toluene diisocyanate TDI of 0. 1996. However, OSHA recommends that employers use exposure Toluene (C₆H₅CH₃) is a colorless liquid with a sweet, pungent odor. OSHA is retaining its limit of 100 ppm (8-hour TWA) for vinyl toluene. Breathing high levels of toluene during pregnancy has been shown to result in children with birth defects and to retard mental abilities and growth. 1000, Table Z-1-A in 1989. This chemical is on the Special Health Hazard Substance List. 5 ppm Basis for revised IDLH: The revised IDLH for toluene-2,4-diisocyanate is 2. Employers are required to keep worker exposures at or below the PEL. 14 mg/m. Laboratory employee exposure to hazardous chemicals such as Toluene, Xylene or Acrylamide. Section 9: Physical and Chemical Oct 3, 2022 · The eight-hour time-weighted average (TWA) OSHA PEL and 15-minute STEL for general industry are 1 ppm [3. 25 L) ***STEL sampling 15 min (0. 2 L/min for a total sample size as shown in Table 3. Class IIIB Combustible Liquid: Fl. 1 ppm. Title: Benzene. 5CH. 75 L) ****120 min (6 L) Toluene TWA: 20 ppm (Vacated) TWA: 100 ppm (Vacated) TWA: 375 mg/m3 Ceiling: 300 ppm (Vacated) STEL: 150 ppm (Vacated) STEL: 560 mg/m 3 TWA: 200 ppm IDLH: 500 ppm TWA: 100 ppm TWA: 375 mg/m3 STEL: 150 ppm STEL: 560 mg/m TWA: 20 ppm Legend ACGIH - American Conference of Governmental Industrial Hygienists OSHA - Occupational Safety and Health NMAM is a collection of methods for sampling and analysis of contaminants in workplace air, and in the blood and urine of workers who are occupationally exposed. The purpose of this evaluation was to validate a sampling and analytical procedure at the 2-ppm level for all three isomers based on methods validated for other aromatic amines. The ACGIH recommends a TWA of 50 ppm with a 100-ppm short-term exposure limit. OSHA’s proposed and final rule limits for TDI are 0. 0. Vinyl toluene is a colorless liquid with a strong, disagreeable odor. 15A], (January 20, 1999). November 1998. How does the federal government regulate toluene to protect health? In occupational settings, the U. 082 4 l . Do not rely on odor alone to determine potentially hazardous exposures. This corresponds to 0. To sample for α-methylstyrene or β-methylstyrene as described in NIOSH method 1501, follow the sampling guidance described in that method. 19 mg/m3] and 5 ppm [15. References The present study demonstrates reductions of dopamine (DA) turnover in various areas of the anterior nucleus caudate of rat by toluene at concentrations lower than the current OSHA threshold limit value (100 ppm). The former OSHA standard for toluene was 200 ppm as an 8-hour TWA limit, with a 300-ppm ceiling (not to be exceeded for more than 10 minutes in any eight-hour period), and a 500-ppm peak. Technical and commercial grades of xylenes often contain substantial amounts of ethylbenzene (10 50%), and perhaps minor amounts of other solvents as well. Samples are desorbed with toluene and analyzed by gas chromatography (GC) using a flame photometric detector (FPD). A level of 4 ppm will cause immediate eye irritation, 4. 75 L) ****120 min (6 L) Nov 27, 2018 · Toluene has a federal OSHA permissible exposure limit, but many people can smell it below its PEL because of its sharp, sweet odor. Up to 400 ppm: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge (s)* (APF = 25) Any powered, air-purifying respirator with organic vapor cartridge (s)* (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor Jun 23, 2022 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. 005 ppm (0. 75 L) ****120 min (6 L) Overview. (l) This 8-hour TWA applies to respirable dust as measured by a vertical elutriator cotton dust sampler or equivalent instrument. 1910. For toluene, this means keeping worker exposure at or below the PEL of 200 parts per million (ppm) of toluene for an 8-hour work shift (29 CFR 1910. 352°F. The sampling time can be increased to 240 min at a sampling rate of 1 L/min. Toluene levels of 500 ppm are considered 52:34460-578. C is the concentration of a particular contaminant. urces. It is also used as a cross-linking agent in the manufacture of nylon polymers. 05 L) and Ceiling sampling 5 min (0. Health and Safety Executive Method 25/2 Hazard. Occupational Safety and The NIOSH Pocket Guide to Chemical Hazards (NPG) informs workers, employers, and occupational health professionals about workplace chemicals and their hazards. K. Calibrate each personal sampling pump with a representative sampler in line. 20 mg/m3 for MDI and 0. 75 L) ****120 min (6 L) The EPA’s reference concentration (RfC) for toluene is 5 mg/m 3 and the EPA’s reference dose (RfD) is 0. 02 ppm. Fact sheet last revised: 2022-07-14. The CDC Agency for Toxic Substances and Disease Registry (ATSDR) established an Acute Minimal Risk Level (MRL) of 2 ppm and a Chronic MRL of 1 ppm in 2017. U. ) Phosgene gas is a severe eye and respiratory irritant. Health effects of isocyanate exposure include irritation of skin and mucous membranes, chest tightness, and difficult breathing. NIOSH: Alert - Preventing asthma and death from diisocyanate exposure. Toluene and Xylene are solvents used to fix tissue specimens and rinse stains, and are primarily found in the histology, hematology, microbiology, and cytology laboratories. Toluene is a clear, colorless liquid which becomes a vapor when exposed to air at room temperature. 05-2% range Exposure Limits OSHA PEL The new PELs for formaldehyde are 1 ppm for the TWA and 2 ppm for the STEL. 8 ppm causes coughing and brief exposure to 50 ppm Apr 2, 2024 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. 1027, is stayed or otherwise not in effect. The ACGIH (1986/Ex. Exposure to toluene may occur from breathing ambient or indoor air affected by such. ) Toluene is a central nervous system depressant. The main source of BTEX contamination to a community is from underground storage tanks Benzene may be present in gasoline and other petroleum products up to 1%, as a natural part of the cracking process. OSHA Technical Manual (OTM). 3. ) 1377: Sampling group: Sampler/Sampling media: Isocyanate Sampling Filter Kit - GFF (37 mm, open-faced) coated with 1 mg 1-(2-pyridyl)piperazine [SLTC103] Sampling time * 15 min. Notes: See 29 CFR 1910. EPA IRIS Methylene Chloride, 2011. 2. 2 There are no other known interferences to the sampling method. 1200) Label Elements Signal Word Danger Hazard Statements Flammable liquid and vapor May be fatal if swallowed and enters airways Company n employee can be exposed to in an 8-hour period. 005 ppm as an 8-hour TWA and 0. -40°F. lvent. Its vapor is heavier than air and may cause asphyxiation in enclosed, poorly ventilated, or low-lying areas. 051 mg/m³) Jun 6, 2022 · follow mfr instructions. n 1968, meaning the existing PELs were once CAS number: 108-88-3. 9 Benzene production was 2. The central nervous system (CNS) is the primary target organ for toluene toxicity in both humans and animals for acute (short-term) and chronic (long Jan 29, 2021 · Sampling time * Sampling volume (TWA) * 100 L. 1028. OSHA notes that Safety Data Sheets provided by suppliers of toluene-containing products must disclose the presence of the liquid, and employers must provide workers with copies of the SDSs. Sample at an accurately known flow rate between 0. REL-TWA . ODOR THRESHOLD=2. Methodology exists which has previously been validated by the OSHA Analytical Laboratory for a basis of OSHA policy. ACGIH TLV (United States, 3/2012). Products that may contain toluene-such as paint, metal cleaners and Details of the supplier of the safety data sheet 2. conc. 3MW: 92. ) Apr 19, 2021 · NIOSH: Current Intelligence Bulletin 53 - Toluene Diisocyanate (TDI) and Toluenediamine (TDA) -Evidence of Carcinogenicity. REASON FOR CITATION * Toluene-2,4-Diisocyanate is on the Hazardous Substance List because it is regulated by OSHA and cited by ACGIH, DOT, NIOSH, NTP, DEP, IARC, NFPA and EPA. * All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete Nov 1, 2022 · Monitoring Methods Used by OSHA. NIOSH REL TWA 100 ppm (375 mg/m 3) ST 150 ppm (560 mg/m 3) OSHA PEL TWA 200 ppm C 300 ppm 500 ppm (10-minute maximum peak The EPA has recommended a drinking water guideline value of 1 mg/L for toluene. OSHA PEL (permissible exposure limit) = 0. 02 ppm as a 15-minute STEL. OSHA sets permissible exposure limits (PELs) to protect workers against adverse health effects resulting from exposure to hazardous substances. After the toluene method was completed, by consensus it was decided that future evaluation work by the OSHA SLTC Methods Development Team for solvent vapors would first address charcoal tubes for active sampling as well as SKC 575-002 Samplers (which contain Anasorb 747) for diffusive sampling. The following references aid in recognizing and evaluating hazards associated with isocyanates in the workplace. The sample is analyzed for chloride (or bromide, if requested) and the result reported as the acid. NMAM is a collection of methods for sampling and analysis of contaminants in workplace air, and in the blood and urine of workers who The RfC for toluene was derived from a series of 10 studies observing neurological effects in workers. 75 L) ****120 min (6 L) Xylenes is a collective term for a mixture of m-, o-, and p- isomers of xylene. 8. 1000 Table Z-2). 1 Apparatus A 6-mm x 70-mm glass sampling tube packed with two sections of 20/40 mesh Anasorb CSC sorbent is required for sampling. It is used to make Polyurethane foams, elastomers and coatings. 2 Sampling Procedure Follow all safety practices that apply to the work area where sampling occurs. Sampling flow rate (TWA) * 1 L/min. Vapor pressure. , impaired color vision, impaired hearing, decreased performance in neurobehavioral analysis, changes in motor and sensory nerve conduction velocity, headache, and dizziness). The sampling parameters and method listed above were developed for STYRENE (VINYL BENZENE; PHENYLETHYLENE) but are appropriate to use for sampling VINYL TOLUENE as well. gx mu yj nz sc da lh rs fz cm